Pain management is a large reason why patients choose to seek out medical treatment. Even if the underlying medical condition is under control, pain prevents patients from carrying on with their daily activities, working productively, or even appreciating in their roles within their families and friend groups. Chronic pain can be difficult to manage, sometimes requiring a different approach to resolve. Optimal treatment may require a combination of multiple drugs compounded into a cream base for topical application at the site of pain. Side effects associated with oral administration can be greatly reduced when medications are used topically. Patients can also avoid gastrointestinal upset usually accompanied by oral pain medications. This treatment regimen gives providers another option for pain management and an opportunity to treat pain without using opioids. Our pharmacists work together with providers and patients to provide a customized topical treatment plan to ultimately achieve relief from chronic pain.