Low-Dose Naltrexone

What is low-dose naltrexone (LDN)?

Naltrexone is an oral medication typically dosed at 50 mg, traditionally intended for use in opioid and alcohol use disorders. Many recent studies focus on the off-label use of naltrexone in lower doses to treat types of pain conditions such as fibromyalgia, complex regional pain syndrome, and diabetic neuropathy. When taken in lower doses, naltrexone is processed differently through the nervous system and acts as a form of relief from inflammatory diseases. It has also been used to treat certain auto-immune conditions, such as Lyme Disease and irritable bowel syndrome.

Naltrexone studies demonstrate that LDN is usually well tolerated, with GI upset and sleep disturbances being the primary potential side effect that patient’s experience. Gradually titrating the dose from as low as 0.5mg up to a target dose of 4.5mg at bedtime, and taking with a small amount of food easily manages these side effects.

Why use PerforMIX for low-dose naltrexone?

-Currently, low-dose naltrexone is only available via compounding pharmacies and is not available as a manufactured product. Therefore, you cannot get LDN through a traditional retail pharmacy.

-Our pharmacists see prescriptions for LDN often, making them a vital resource for LDN counseling.

-PerforMIX holds multiple accreditations from third-party testing associations that prove our dedication to efficacy, medication safety, and customer satisfaction.

-We can ship LDN prescriptions right to patient’s doorstep!

Low-Dose Naltrexone Research Trust Member

We are proud to be partnered with the LDN (Low-Dose Naltrexone) Research Trust to help educate patients and providers on the benefits of Low-Dose Naltrexone. The primary aim of the LDN Research Trust is to initiate clinical trials of Low-Dose Naltrexone for autoimmune diseases and cancer treatment. By raising awareness of LDN, we can see more people benefit from LDN when applicable to their condition.